A marked NYPD vehicle slammed into a private bus hard enough to send the coach careening into a parked delivery truck and the side of a hotel, leaving two people injured, cops said.
The police SUV was traveling south on Broadway when it struck the white bus at Walker Street around 5:50 a.m., cops said.
The bus was pushed into the delivery truck at the corner of the Walker Hotel Tribeca.
The 49-year-old driver and 36-year-old passenger inside the truck were taken to New York Downtown Hospital in stable condition, cops said.
People who were on the bus left before police arrived and the 60-year-old bus driver was uninjured, cops said. The police officer was taken to a local hospital in stable condition, cops said.
The police cruiser’s siren was blaring, a witness said.
“We were opening up our coffee shop this morning and out of nowhere I heard a police siren wailing really fast and then simultaneously a bus was coming, crossing the street and they immediately full-force collided,” said Nick Varsames, who works at Blue Bottle Coffee in the hotel. 
“The bus came right at the banister by the window and crashed and shook the building,” he said. “It was just very sudden.” 
The truck that was struck was delivering food to the coffee shop, he said.
The police officer was on his way to pick up another officer at Manhattan Central Booking at 100 Center St., cops said.
The collision broke off a slab of the historic building’s facade, photos from the scene show. The structure, built in 1899, was formerly a button and ribbon factory.
“A few of the hotel residents came down because they felt the shake upstairs when they were waking up,” Varsames, the barista, said. “It just kind of rattled the place.”
The cause of the crash was under investigation, police said.

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