The crash occurred in Common Lane in the early hours of Thursday
Two women in their 20s have died in a crash that also left a nine-year-old boy with life-changing injuries.
A further three men, who were travelling in a second car involved in the crash in Pleasley, on the Derbyshire-Nottinghamshire border, at about 06:20 GMT on Thursday suffered injuries, with two in a serious condition, Derbyshire Police said.
An 18-year-old man was arrested at the scene in Common Lane on suspicion of causing death by dangerous driving, before being taken to hospital due to injuries he sustained in the crash.
Police have asked for witnesses who saw the two cars involved, a Suzuki Alto and Vauxhall Meriva, to make contact.
The force said the women's families "are aware and our thoughts are with them".
The road was shut between the A617 and Meadow Lane while emergency services worked at the scene.
Fire crews from stations in Derbyshire and Nottinghamshire were also sent to the scene.
The road remained closed into Thursday afternoon with drivers asked to find alternative routes.
Tell us which stories we should cover in Derby
Follow BBC Derby on Facebook, external, on X, external, or on Instagram, external. Send your story ideas to eastmidsnews@bbc.co.uk, external or via WhatsApp, external on 0808 100 2210.
Derbyshire Fire and Rescue Service
Derbyshire Police
Coca-Cola Christmas Truck Tour 2025 makes stop in Burton-on-Trent
Protesters set to go head-to-head at Chesterfield asylum seeker hotel for second time
Road was closed for several hours after two women died in crash
“Jealous” and “obsessed” Chesterfield man destroyed former partner’s home by setting it alight, court hears
Buxton’s New Inn pub won Camra award after being open less than a year
Four men arrested following armed robbery in New Mills
Labour ditches day-one protection from unfair dismissal in U-turn
Households face 'dismal' rise in spending power, says IFS
Starmer could have scrapped child benefit cap last year – why did he wait?
'I am devastated': Hong Kong residents in disbelief after fire destroys blocks of flats
Stranger Things return gives some critics chills and thrills, but leaves others lukewarm
Faisal Islam: The real reason Reeves is making you pay more tax
Isas, cars and pensions: How the Budget affects you
Year after ceasefire, peace eludes south Lebanon as Israeli strikes continue
What's the real cost of cheap, fake football shirts?
Australia's beloved weather website got a makeover – and infuriated users
'I panic every time she coughs' – Delhi's toxic air is making its children sick
Off Air with Laura K: Get Laura Kuenssberg’s weekly newsletter emailed directly to you
Roman and Tyler dive into their Race Across the World rivalry
The story of Britain’s biggest mass water poisoning
A group of teenage goths get more than they bargained for
Kate's life takes an upward turn, but is it too good to be true?
Labour ditches day-one protection from unfair dismissal in U-turn
Putin doubles down on demands for Ukrainian territory ahead of talks with US in Moscow
Celebrity Traitors star Ruth Codd recovering after second leg amputation
Households face 'dismal' rise in spending power, says IFS
Man, 31, arrested over Manchester synagogue attack
'Hang in there': Agonising wait for the missing after Hong Kong blaze
Starmer could have scrapped child benefit cap last year – why did he wait?
Sharp fall in UK net migration with drop in arrivals for work and study
Faisal Islam: The real reason Reeves is making you pay more tax
France to bring in form of military service, 25 years after conscription was phased out
Copyright © 2025 BBC. The BBC is not responsible for the content of external sites. Read about our approach to external linking.

source